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Monolith X
Monolith X

Monolith X

Dual Technology. Zero Immobilization. Ultimate Confidence.

Monolith X redefines how you measure molecular interactions — directly in solution, with no immobilization, no complex assay setup, and virtually no sample loss. Equipped with Spectral Shift and MST biophysical technologies, Monolith X is your go-to instrument for rapid, high-confidence Kd measurements, even when SPR and other platforms fall short.

With ultra-low sample consumption, intuitive software, and fluidics-free operation, Monolith X enables scientists to analyze the toughest molecular interactions — from weak binders and IDPs to covalent interactions and crude samples — effortlessly.

If you’re seeking a reliable orthogonal tool or a primary system for binding affinity characterization, Monolith X delivers fast, reproducible data, superior versatility, and minimal downtime — making it an asset for any lab pushing the boundaries of biophysics, drug discovery, or protein research.

 

 

Enquiry

Why Choose Monolith?

  • No sensor chips, consumables, or routine service required
  • Fast results — typically in under 30 minutes
  • Trusted by global leaders in research and development
  • Validated by users across pharma, biotech, and academia
  • Small footprint, huge capability — ideal for any lab size

Retail-Focused Highlights

  • Dual Tech Power
    Combines Spectral Shift and MST for unmatched interaction analysis.
  • No Immobilization Needed
    Skip chips and matrices — measure binding directly in solution.
  • Sample-Sparing & Buffer-Friendly
    Use tiny sample volumes, even in complex buffers or crude lysates.
  • Works with Nearly Any Molecule
    From small compounds to IDPs, membrane proteins, and PROTACs.
  • SPR Alternative & Validator
    Handle tough interactions and confirm SPR data effortlessly.
  • Maintenance-Free Design
    No fluidics, no cleaning — just load, run, and get results.
  • Rapid & User-Friendly
    Easy software and fast runs mean you’re productive on day one.

Ideal For

  • Pharma & Biotech R&D
    Binding kinetics, hit validation, fragment screening, and beyond — all with minimal assay prep.
  • Academic Core Labs
    Low-touch, reliable instrumentation for diverse users and sample types.
  • Structural Biology & Biophysics
    Study protein-protein interactions, conformational dynamics, and more with full flexibility.
  • Diagnostics & Assay Development
    Fast-track development with reduced sample volumes and robust assay reproducibility.
  • Spectral Shift Technology: Dual-wavelength spectral tracking (650nm & 670nm) detects even subtle binding-induced changes in emission profiles.
  • Microscale Thermophoresis (MST): Analyzes molecular movement in response to heat gradients — a powerful readout for molecular binding events.

Contact Us at +9714 2152799

We can help you with a solution tailor to your specific need.